3-(Dimethylamino)propyl chloride hydrochloride → Dimaprit hydrochloride
反応式
[NH2:1][C:2]([NH2:4])=[S:3].[ClH:5].[CH3:6][N:7]([CH3:12])[CH2:8][CH2:9][CH2:10][Cl:11]>C(O)C>[ClH:11].[ClH:5].[CH3:6][N:7]([CH3:12])[CH2:8][CH2:9][CH2:10][S:3][C:2](=[NH:4])[NH2:1]参加物
4
実験手順
Equimolar quantities of thiourea and 3-(dimethylamino)-1-chloropropane hydrochloride and a little ethanol are heated together at 140° for 3 hours, and the cooled mixture is recrystallised from methanol/isopropanol to give the title product.
後処理
- customthe cooled mixture is recrystallised from methanol/isopropanol
出典と根拠
- ORDレコード
- ord-9062996cf30a4f2d8df7903bf697b00e
- 出典データセット
- uspto-grants-1978_11
- 特許番号
- US04126670
反応ノート
読み込み中…