2-Amino-4,6-dimethoxy-1,3,5-triazine → N-[(4,6-dimethoxy-1,3,5-triazin-2-yl)aminocarbonyl]-2-chlorobenzenesulfonamide

HRID 1704612

反応式

HRID 1704612 の反応式
[NH2:1][C:2]1[N:7]=[C:6]([O:8][CH3:9])[N:5]=[C:4]([O:10][CH3:11])[N:3]=1.[Cl:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[S:19]([N:22]=[C:23]=[O:24])(=[O:21])=[O:20]>C(Cl)Cl>[CH3:9][O:8][C:6]1[N:5]=[C:4]([O:10][CH3:11])[N:3]=[C:2]([NH:1][C:23]([NH:22][S:19]([C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[Cl:12])(=[O:20])=[O:21])=[O:24])[N:7]=1

参加物

4

反応物 2

HCID 278402-Amino-4,6-dimethoxy-1,3,5-triazineHCID 174071Benzenesulfonyl isocyanate, 2-chloro-

生成物 1

HCID 14835175N-[(4,6-dimethoxy-1,3,5-triazin-2-yl)aminocarbonyl]-2-chlorobenzenesulfonamide

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

To 15.6 g of 2-amino-4,6-dimethoxy-1,3,5-triazine in 300 ml of dry methylene chloride containing 0.1 g 1,4-diazabicyclo[2,2,2]octane was added 21 g 2-chlorobenzenesulfonyl isocyanate with stirring. The mixture was stirred for 16 hours and the resultant solid was removed by filtration. After washing the solid with 1-chlorobutane, the resulting product, N-[(4,6-dimethoxy-1,3,5-triazin-2-yl)-aminocarbonyl]-2-chlorobenzenesulfonamide melted at 188°-189° C. Infrared absorption analysis showed absorption peaks at 1740 cm-1, 1630 cm-1 and 1595 cm-1 which are typical for this type of compound.

後処理

  1. stirringThe mixture was stirred for 16 hours
  2. customthe resultant solid was removed by filtration
  3. washAfter washing the solid with 1-chlorobutane
  4. customabsorption analysis
  5. customabsorption peaks at 1740 cm-1, 1630 cm-1 and 1595 cm-1 which

出典と根拠

ORDレコード
ord-3f5511fb26d5403e9c89d6032cc99f9b
出典データセット
uspto-grants-1978_11
特許番号
US04127405

関連ノート

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