化工社化工社 化学情報印刷レポート · 研究参考用
Diethylamine → Glycine, N,N-diethyl-, 4-(acetylamino)phenyl ester, hydrochloride (1:1)
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diethylamine | HCID 8021 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | 4-Acetamidophenyl chloroacetate | HCID 13277664 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Glycine, N,N-diethyl-, 4-(acetylamino)phenyl ester, hydrochloride (1:1) | HCID 108082 | 39.8% |
反応手順
22.8 g of p-acetamidophenyl chloroacetate were added in small portions to a solution of 7.5 g of diethylamine in 30 c.c. of triethylamine with stirring, while the temperature was maintained at between 40° C. and 50° C. with a bath of cold water if necessary. The process described in Example 1 was then followed to obtain 12 g of p-acetamidophenyl diethylaminoacetate hydrochloride melting point = 228° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04127671 |
| 出典データセット | uspto-grants-1978_11 |
| ORD ID | ord-abc1d9f1c5e84e8e9fbe8e110565d271 |
| 出典メモ | uspto-grants-1978_11 |