N,N-Diethylethylenediamine → N(2-diethylaminoethyl)-5-butanoyl-2-methoxybenzamide

HRID 1704743ノート

反応式

HRID 1704743 の反応式
[C:1]([C:6]1[CH:7]=[C:8](C)[C:9]([O:15][CH3:16])=[C:10]([CH:14]=1)[C:11]([O-:13])=O)(=[O:5])[CH2:2][CH2:3][CH3:4].[CH2:18]([N:20]([CH2:23][CH2:24][NH2:25])[CH2:21][CH3:22])[CH3:19]>>[CH2:18]([N:20]([CH2:21][CH3:22])[CH2:23][CH2:24][NH:25][C:11](=[O:13])[C:10]1[CH:14]=[C:6]([C:1](=[O:5])[CH2:2][CH2:3][CH3:4])[CH:7]=[CH:8][C:9]=1[O:15][CH3:16])[CH3:19]

参加物

3

反応物 2

HCID 60993N,N-DiethylethylenediamineHCID 131711354HCID 131711354、化合物

生成物 1

HCID 22758666N(2-diethylaminoethyl)-5-butanoyl-2-methoxybenzamide

反応条件

温度
100 °C

実験手順

In a flask equipped with a Dean-Stark device, there are introduced 10 g of the ester obtained in Example 3 and 10 g of diethylaminoethylamine and the mixture is heated to 100° C. for 3 hours. There are thus obtained 10.3 g of an oily product which is converted to hydrochlorate in the ethanol-ether mixture. The product obtained has a melting point of 155° C.

後処理

  1. customIn a flask equipped with a Dean-Stark device, there
  2. customThe product obtained

出典と根拠

ORDレコード
ord-94b420d4f1e54880809f23c890fcdd16
出典データセット
uspto-grants-1978_11
特許番号
US04127666

反応ノート

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