化工社化工社 化学情報印刷レポート · 研究参考用
Fosmidomycin → Fosmidomycin
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Fosmidomycin | HCID 572 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Potassium Alum | HCID 24856 | — |
| 反応物 | Sodium | HCID 5360545 | — |
| 生成物 | Fosmidomycin | HCID 572 | 74% |
| 生成物 | Aluminum | HCID 5359268 | — |
反応手順
To an aqueous solution (45 ml.) of potassium alum (9.17 g.) was added mono sodium salt of 3-(N-formyl-N-hydroxyamino)propylphosphonic acid (3.08 g.) with stirring, and the solution was adjusted to pH 6-7 with 10% aqueous sodium hydroxide solution and then stirred for 2 hours at ambient temperature. The precipitating materials were collected by filtration, washed twice with water (each 10 ml.) and dried to give aluminum salt of 3-(N-formyl-N-hydroxyamino)propylphosphonic acid (2.28 g.).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04206156 |
| 出典データセット | uspto-grants-1980_06 |
| ORD ID | ord-b587d404e39a46bf913f82d39f50caeb |
| 出典メモ | uspto-grants-1980_06 |