HCID 57178653、化合物 → N-methyl-4,5,6,7-tetrahydrobenzo[d]thiazol-4-amine
反応式
[CH3:1][N:2]=[C:3]1[C:8]2[N:9]=[CH:10][S:11][C:7]=2[CH2:6][CH2:5][CH2:4]1.[H][H]>C(O)C.[Pt]=O>[CH3:1][NH:2][CH:3]1[C:8]2[N:9]=[CH:10][S:11][C:7]=2[CH2:6][CH2:5][CH2:4]1参加物
5
実験手順
Catalytic hydrogenation of the 4-methylimino derivative obtained in step (e) in ethanol containing excess methylamine, in the presence of platinum oxide, proceeds slowly at 50° C. under ordinary pressure. After the theoretical amount of hydrogen has been taken up, the solution is filtered, evaporated, and the residue is distilled: B.p.0.4 =86°-88° C.; Yield; 80%.
後処理
- customslowly at 50° C.
- filtrationthe solution is filtered
- customevaporated
- distillationthe residue is distilled
- customB.p.0.4 =86°-88° C.
出典と根拠
- ORDレコード
- ord-803c985a363042a7a7bf760c26591dde
- 出典データセット
- uspto-grants-1980_06
- 特許番号
- US04208420
反応ノート
読み込み中…