Water → 1-(3,4-Methylenedioxyphenyl)-4-morpholino-1-butene-3-ol
反応式
[CH2:1]1[O:9][C:8]2[CH:7]=[CH:6][C:5]([CH:10]=[CH:11][C:12](=[O:20])[CH2:13][N:14]3[CH2:19][CH2:18][O:17][CH2:16][CH2:15]3)=[CH:4][C:3]=2[O:2]1.O>CO>[CH2:1]1[O:9][C:8]2[CH:7]=[CH:6][C:5]([CH:10]=[CH:11][CH:12]([OH:20])[CH2:13][N:14]3[CH2:15][CH2:16][O:17][CH2:18][CH2:19]3)=[CH:4][C:3]=2[O:2]1参加物
4
実験手順
27.5 g of the ketone (0.1 M) obtained in Example 1 is dissolved in 300 cm3 of methanol and an aqueous solution of KBH4 is added dropwise. The reaction mixture is left overnight and decomposed with water. The product obtained is filtered and recrystallised in ethanol.
後処理
- additionan aqueous solution of KBH4 is added dropwise
- customThe product obtained
- filtrationis filtered
- customrecrystallised in ethanol
出典と根拠
- ORDレコード
- ord-842c2a0ae5a34c11a258e3a737fab6a7
- 出典データセット
- uspto-grants-1980_06
- 特許番号
- US04209517
反応ノート
読み込み中…