Ethyl orthoformate → 6-Phenyl-1,2,4-triazolo[4,3-a]pyrimidine
反応式
[NH:1]([C:3]1[N:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:5][N:4]=1)[NH2:2].[CH:15](OCC)(OCC)OCC>>[C:9]1([C:6]2[CH:7]=[N:8][C:3]3[N:4]([CH:15]=[N:2][N:1]=3)[CH:5]=2)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1参加物
3
実験手順
A mixture of 2.5 g. of 2-hydrazino-5-phenylpyrimidine and 25 ml. of triethyl orthoformate is heated for 16 hours under reflux. The material that separates is collected and crystallized from ethanol to give 1.5 g. of the product of the Example, m.p. 231° C.
後処理
- additionA mixture of 2.5 g
- temperatureunder reflux
- customThe material that separates is collected
- customcrystallized from ethanol
- customto give 1.5 g
出典と根拠
- ORDレコード
- ord-9a4192171b444a14a381a1fef4bfd061
- 出典データセット
- uspto-grants-1980_06
- 特許番号
- US04209621
反応ノート
読み込み中…