6-Phenyl-1,2,4-triazolo[4,3-a]pyrimidine → 6-(Phenyl)-1,2,4-triazolo[1,5-a]pyrimidine

HRID 1707047ノート

反応式

HRID 1707047 の反応式
[C:1]1([C:7]2[CH:8]=[N:9][C:10]3[N:11]([CH:13]=[N:14][N:15]=3)[CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>C(O)=O>[C:1]1([C:7]2[CH:8]=[N:9][C:10]3[N:15]([N:14]=[CH:13][N:11]=3)[CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

3

反応物 1

HCID 203333416-Phenyl-1,2,4-triazolo[4,3-a]pyrimidine

生成物 1

HCID 100813826-(Phenyl)-1,2,4-triazolo[1,5-a]pyrimidine

試薬・触媒・溶媒 1

HCID 284Formic Acid溶媒

実験手順

A mixture of 1.0 g. of 6-(phenyl)-1,2,4-triazolo[4,3-a]pyrimidine and 10 ml. of 97% formic acid is refluxed for 5 hours and the excess formic acid is removed under reduced pressure. The solid residue is collected, washed with hexane and recrystallized from glacial acetic acid to give the product as crystals, m.p. 164°-167° C.

後処理

  1. additionA mixture of 1.0 g
  2. customthe excess formic acid is removed under reduced pressure
  3. customThe solid residue is collected
  4. washwashed with hexane
  5. customrecrystallized from glacial acetic acid

出典と根拠

ORDレコード
ord-b6f8ba44ce114f2c87513d73709ee6a4
出典データセット
uspto-grants-1980_06
特許番号
US04209621

反応ノート

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