Acetic Acid → 6-(Phenyl)-1,2,4-triazolo[1,5-a]pyrimidine

HRID 1707048ノート

反応式

HRID 1707048 の反応式
[C:1]1([C:7]([CH2:9]C=O)=N)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:12][C:13]1[N:17]=[CH:16][NH:15][N:14]=1.[C:18](O)(=O)C>>[C:1]1([C:7]2[CH:9]=[N:12][C:13]3[N:14]([N:15]=[CH:16][N:17]=3)[CH:18]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

4

反応物 3

HCID 176Acetic AcidHCID 86737068(Phenyl)formimidoylacetaldehydeHCID 178418311HCID 178418311、化合物

生成物 1

HCID 100813826-(Phenyl)-1,2,4-triazolo[1,5-a]pyrimidine

実験手順

An equimolar mixture of (phenyl)formimidoylacetaldehyde and 3-amino-1,2,4-triazole in glacial acetic acid (5 ml. acetic acid to 0.01 mole of reagents) is refluxed for 2 hours and allowed to cool to room temperature. The solid which separates is collected, washed with glacial acetic acid and dried. The solid is recrystallized from glacial acetic acid to give the product, m.p. 164°-167° C.

後処理

  1. temperatureis refluxed for 2 hours
  2. customThe solid which separates is collected
  3. washwashed with glacial acetic acid
  4. customdried
  5. customThe solid is recrystallized from glacial acetic acid
  6. customto give the product, m.p. 164°-167° C.

出典と根拠

ORDレコード
ord-283ad2879ae04803951bae3c9283c4f9
出典データセット
uspto-grants-1980_06
特許番号
US04209621

反応ノート

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