(Pyrimidin-5-yl)boronic acid → (1E,4E)-ethyl 2-amino-8-(pyrimidin-5-yl)-3H-benzo[b]azepine-4-carboxylate

HRID 170746

反応式

[NH2:1][C:2]1=[N:8][c:7]2[c:6]([cH:12][cH:11][c:10]([Br:13])[cH:9]2)[CH:5]=[C:4]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[CH2:3]1.[n:19]1[cH:20][n:21][cH:22][c:23]([B:25]([OH:26])[OH:27])[cH:24]1>>[NH2:1][C:2]1=[N:8][c:7]2[c:6]([cH:12][cH:11][c:10](-[c:23]3[cH:22][n:21][cH:20][n:19][cH:24]3)[cH:9]2)[CH:5]=[C:4]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[CH2:3]1