2,3-Dimethyl-4-hydroxy-7-methoxyindole → 4-methoxy-2,3-dimethyl-1H-indol-7-ol

反応式

C([O:8][C:9]1[CH:10]=[CH:11][C:12]([O:20][CH3:21])=[C:13]2[C:17]=1[NH:16][C:15]([CH3:18])=[C:14]2[CH3:19])C1C=CC=CC=1.CC1NC2C(C=1C)=C(O)C=CC=2OC>>[CH3:18][C:15]1[NH:16][C:17]2[C:13]([C:14]=1[CH3:19])=[C:12]([O:20][CH3:21])[CH:11]=[CH:10][C:9]=2[OH:8]

参加物

反応物 2

HCID 184594912,3-Dimethyl-4-hydroxy-7-methoxyindole

HCID 189625287-Benzyloxy-2,3-dimethyl-4-methoxyindole

生成物 1

HCID 212009824-methoxy-2,3-dimethyl-1H-indol-7-ol

実験手順

2,3-Dimethyl-7-hydroxy-4-methoxyindole is prepared from 7-benzyloxy-2,3-dimethyl-4-methoxyindole according to the operating method described for the preparation of 2,3-dimethyl-4-hydroxy-7-methoxyindole (Example 7c). It melts at 159° C.

出典と根拠

ORDレコード: ord-aad72515bd3741e79776307c528c6d27
出典データセット: uspto-grants-1994_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05354870

反応ノート

読み込み中…