5-Acetoxyacetamido-3-methylcarbamoyl2,4,6-triiodobenzoyl chloride → N-(2,3-dihydroxypropyl)-5-[2,3-diacetoxypropionylamino)-N'-methyl-2,4,6-triiodoisophthalamide

HRID 1707905ノート

反応式

HRID 1707905 の反応式
[C:1]([O:4][CH:5]([CH2:25][O:26][C:27](=[O:29])[CH3:28])[C:6]([NH:8]C1C(I)=C(C(=O)NC)C(I)=C(C=1I)C(Cl)=O)=[O:7])(=[O:3])[CH3:2].[OH:30][CH:31]([CH2:57][OH:58])[CH2:32][N:33](NC(=O)C)[C:34](=[O:52])[C:35]1[C:44]([I:45])=[C:43](OC(=O)C)[C:42]([I:50])=[C:37]([C:38]([NH:40][CH3:41])=[O:39])[C:36]=1[I:51].C(OCC(NC1C(I)=C(C(=O)NC)C(I)=C(C=1I)C(Cl)=O)=O)(=O)C>>[OH:30][CH:31]([CH2:57][OH:58])[CH2:32][NH:33][C:34](=[O:52])[C:35]1[C:44]([I:45])=[C:43]([NH:8][C:6](=[O:7])[CH:5]([O:4][C:1](=[O:3])[CH3:2])[CH2:25][O:26][C:27](=[O:29])[CH3:28])[C:42]([I:50])=[C:37]([C:38]([NH:40][CH3:41])=[O:39])[C:36]=1[I:51]

参加物

4

反応物 3

HCID 156706225-Acetoxyacetamido-3-methylcarbamoyl2,4,6-triiodobenzoyl chlorideHCID 189602905-(2,3-Diacetoxypropionylamino)-3-methylcarbamoyl-2,4,6-triiodobenzoyl chlorideHCID 86748190N-(2,3-dihydroxypropyl)-5-acetoxy-acetamido-N'-methyl-2,4,6-triiodoisophthalamide

生成物 1

HCID 86748189N-(2,3-dihydroxypropyl)-5-[2,3-diacetoxypropionylamino)-N'-methyl-2,4,6-triiodoisophthalamide

実験手順

Compound (12) is prepared from compound (11) in the same manner according to the procedure described for the preparation of compound (4) from compound (3) in Example I, C.

出典と根拠

ORDレコード
ord-ac0a11267a894de5a74ba0a74983a8be
出典データセット
uspto-grants-1994_10
特許番号
US05356613

反応ノート

読み込み中…