化工社化工社 化学情報印刷レポート · 研究参考用
17beta-(Hydroxymethyl)androst-4-ene-3-ol → 17beta-Hydroxymethyl-4-androsten-3-on
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 17beta-(Hydroxymethyl)androst-4-ene-3-ol | HCID 14801334 | — |
| 触媒 | HCID 178418406 | HCID 178418406 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | 17beta-Hydroxymethyl-4-androsten-3-on | HCID 14377617 | 96.6% |
反応手順
A solution of 17β-(hydroxymethyl)-androst-4-ene-3-ol (27 g, 0.089 mol) in 1200 ml trichloromethane was treated with activated manganese dioxide (66 g). After 3 hours the mixture was filtered. Concentration afforded 26 g (96%) of 3-oxo-17β-(hydroxymethyl)-4androstene (m.p. 151° C.).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04946834 |
| 出典データセット | uspto-grants-1990_08 |
| ORD ID | ord-8ee8a3c67fd340aa93ac5c712520c99e |
| 出典メモ | uspto-grants-1990_08 |