Hydrochloric Acid → 2,3-Dibutoxy-6-chloronaphthalene-1,4-dione
反応式
Cl[C:2]1[C:3](=[O:15])[C:4]2[C:9]([C:10](=[O:13])[C:11]=1Cl)=[CH:8][C:7]([Cl:14])=[CH:6][CH:5]=2.Cl>CN(C)C=O>[CH2:10]([O:13][C:2]1[C:3](=[O:15])[C:4]2[C:9]([C:10](=[O:13])[C:11]=1[O:15][CH2:3][CH2:4][CH2:5][CH3:6])=[CH:8][C:7]([Cl:14])=[CH:6][CH:5]=2)[CH2:9][CH2:8][CH3:7]参加物
4
実験手順
To a solution of sodium-n-butoxide (25.8 g) in dry dimethylformamide (125 ml) was added 2,3,6-trichloro-1,4-naphthoquinone (28 g) in one amount. The mixture was refluxed for 2 hours, then cooled, acidified with 6M hydrochloric acid and evaporated. The residue was chromatographed over silica gel using dichloromethane as eluant to yield 2,3-di-n-butoxy-6-chloro-1,4-naphthoquinone (12.3 g) as a red oily solid.
後処理
- temperatureThe mixture was refluxed for 2 hours
- temperaturecooled
- customevaporated
- customThe residue was chromatographed over silica gel
出典と根拠
- ORDレコード
- ord-ff5029b4256c446c82950ac7d8d75403
- 出典データセット
- uspto-grants-1990_08
- 特許番号
- US04946845
反応ノート
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