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HRID 1709086作成日:2026年10月27日

1,1,3-Trichloro-1,2,2,3,3-pentafluoropropane → 1,3-Dichloro-1,1,2,2,3-pentafluoropropane

https://huagongshe.com/reaction/1709086

反応式

関与物質

役割名称HCID仕込み量
反応物1,1,3-Trichloro-1,2,2,3,3-pentafluoropropaneHCID 74244—
溶媒IsopropanolHCID 3776—
生成物1,3-Dichloro-1,1,2,2,3-pentafluoropropaneHCID 62353—

反応手順

For example, to prepare 1,3-dichloro-1,1,2,2,3-pentafluoropropane, 2,2,3,3-tetrafluoropropanol, tosyl chloride, and water are reacted together to form 2,2,3,3-tetrafluoropropyl p-toluenesulfonate. Then, N-methylpyrrolidone, potassium fluoride, and the 2,2,3,3-tetrafluoropropyl p-toluenesulfonate are reacted together to form 1,1,2,2,3-pentafluoropropane. Then, chlorine and the 1,1,2,2,3-pentafluoropropane are reacted to form 1,1,3-trichloro-1,2,2,3,3-pentafluoropropane. Finally, isopropanol and the 1,1,3-trichloro-1,2,2,3,3-pentafluoropropane are reacted to form 1,3-dichloro-1,1,2,2,3-pentafluoropropane.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US04947881
出典データセットuspto-grants-1990_08
ORD IDord-add53b74b1bb42179fb853d922c7fbad
出典メモuspto-grants-1990_08