(Dimethylamino)ethyl methacrylate → 4-Benzoyl-N,N-dimethyl-N-(2-(2-methyl-1-oxo-2-propenyloxy)ethyl)benzenemethanaminium chloride

HRID 1709277

反応式

HRID 1709277 の反応式
[C:1]([O:6][CH2:7][CH2:8][N:9]([CH3:11])[CH3:10])(=[O:5])[C:2]([CH3:4])=[CH2:3].[Cl:12][CH2:13][C:14]1[CH:27]=[CH:26][C:17]([C:18]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[O:19])=[CH:16][CH:15]=1>CC(C)=O>[Cl-:12].[C:18]([C:17]1[CH:26]=[CH:27][C:14]([CH2:13][N+:9]([CH3:11])([CH3:10])[CH2:8][CH2:7][O:6][C:1](=[O:5])[C:2]([CH3:4])=[CH2:3])=[CH:15][CH:16]=1)(=[O:19])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

参加物

4

反応物 2

HCID 17869(Dimethylamino)ethyl methacrylateHCID 30163764-(Chloromethyl)benzophenone

生成物 1

HCID 867441444-Benzoyl-N,N-dimethyl-N-(2-(2-methyl-1-oxo-2-propenyloxy)ethyl)benzenemethanaminium chloride

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

Dimethylaminoethyl methacrylate (10.13 mls) was added to a stirred solution of 4-chloromethylbenzophenone (11.52g) in acetone (50 mls) at 48° C. and the mixture was stirred for fifteen hours at 48°±2° C. The stirred mixture was cooled in an ice bath for two hours prior to filtration, washing with acetone (X2) and drying under vacuo at room temperature. The crude title compound was obtained as a white crystalline solid (16.82g; m.p. 163°-166° C.) which was recrystallised from a mixture of acetone (30 mls) and isopropanol (30 mls).

後処理

  1. temperatureThe stirred mixture was cooled in an ice bath for two hours
  2. filtrationto filtration
  3. washwashing with acetone (X2)
  4. customdrying under vacuo at room temperature

出典と根拠

ORDレコード
ord-a8edc93285a14aa18dd18de117b26d5b
出典データセット
uspto-grants-1990_08
特許番号
US04948819

関連ノート

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