4-Methyl-1,3-oxazolidin-2-one → N-[2-[4-(3,5-dimethyl-2-pyridinyl)piperazine-1-carbonyl]-5-(4-methyl-2-oxo-1,3-oxazolidin-3-yl)phenyl]methanesulfonamide

反応式

[Br:1][c:2]1[cH:3][cH:4][c:5]([C:13](=[O:14])[N:15]2[CH2:16][CH2:17][N:18]([c:21]3[n:22][cH:23][c:24]([CH3:28])[cH:25][c:26]3[CH3:27])[CH2:19][CH2:20]2)[c:6]([NH:8][S:9](=[O:10])(=[O:11])[CH3:12])[cH:7]1.[CH3:29][CH:30]1[NH:31][C:32](=[O:35])[O:33][CH2:34]1>>[c:2]1([N:31]2[CH:30]([CH3:29])[CH2:34][O:33][C:32]2=[O:35])[cH:3][cH:4][c:5]([C:13](=[O:14])[N:15]2[CH2:16][CH2:17][N:18]([c:21]3[n:22][cH:23][c:24]([CH3:28])[cH:25][c:26]3[CH3:27])[CH2:19][CH2:20]2)[c:6]([NH:8][S:9](=[O:10])(=[O:11])[CH3:12])[cH:7]1

参加物

反応物 2

HCID 98554554-Methyl-1,3-oxazolidin-2-one

HCID 58484868N-{5-bromo-2-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}methanesulfonamide

生成物 1

HCID 76800488N-[2-[4-(3,5-dimethyl-2-pyridinyl)piperazine-1-carbonyl]-5-(4-methyl-2-oxo-1,3-oxazolidin-3-yl)phenyl]methanesulfonamide

出典と根拠

ORDレコード: ord-1bda8a7507064dc88df68d1ff331b325
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…