Methanol → 2,2,3-Trifluoro-3-(heptafluoropropoxy)propan-1-ol

反応式

[C:1]([O:11][C:12](=[C:14]([F:16])[F:15])[F:13])([C:4]([C:7]([F:10])([F:9])[F:8])([F:6])[F:5])([F:3])[F:2].CO.[C:19]([O:24]OC(=O)C1C=CC=CC=1)(CC)(C)C>>[C:1]([O:11][CH:12]([C:14]([CH2:19][OH:24])([F:15])[F:16])[F:13])([C:4]([C:7]([F:10])([F:9])[F:8])([F:6])[F:5])([F:3])[F:2]

参加物

反応物 3

HCID 887Methanol

HCID 15388Perfluoro propyl vinyl ether

HCID 78267tert-Pentyl perbenzoate

生成物 1

HCID 125416752,2,3-Trifluoro-3-(heptafluoropropoxy)propan-1-ol

実験手順

C3F7OCFHCF2CH2OH was prepared by the reaction of C3F7OCF═CF2 (53 g, 0.2 mol) with methanol (63.7 g, 2.0 mol) using t-amylperoxybenzoate (1.0 g) as free radical initiator at 106° C. The product reaction mixture was washed with water and distilled and the distillation fraction of b.r.=115-117° C. used in the next step.