ホームMCPワークベンチSkills
ホームワークベンチ通知マイページ
llms.txt · MCPガイドプライバシーポリシー · 利用規約 · サポートv1.8.0
  1. ホーム
  2. /反応

Triethylamine → Phenoxyacetic Acid

HRID 1710306
ノート
印刷プレビュー

反応式

HRID 1710306 の反応式
[N+]([O-])([O-])=O.[Nd+3:5].[N+]([O-])([O-])=O.[N+]([O-])([O-])=O.[O:14]([CH2:21][C:22]([OH:24])=[O:23])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.C(N(CC)CC)C>CO>[Nd:5].[O:14]([CH2:21][C:22]([OH:24])=[O:23])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1
参加物反応条件実験手順後処理出典と根拠反応ノート

参加物

6

反応物 3

HCID 8471TriethylamineHCID 19188Phenoxyacetic AcidHCID 10980413Neodymium(3+) hydrate trinitrate3 回

生成物 2

HCID 19188Phenoxyacetic AcidHCID 23934Neodymium

試薬・触媒・溶媒 1

HCID 887Methanol溶媒3 回

反応条件

温度
25 °C

実験手順

The compound was synthesized by the same method as that for Synthesis Example 1-2 above, that is, after forming a triethylamine salt of phenoxyacetic acid in anhydrous methanol, a methanol solution of neodymium nitrate was added while stirring. Specifically, a reactor similar to that of 1-1 was used to stir a solution obtained by adding 100 ml of an anhydrous methanol to 45.65 g (0.3 mol) of phenoxyacetic acid, while dripping 30.4 g (0.3 mol) of triethylamine while maintaining at 25° C. by cooling in an ice water bath. After dripping, the solution was heated for 30 minutes at 40° C. to prepare a transparent synthesis solution of phenoxyacetic acid-triethylamine salts. Next, this synthesis solution was maintained at about 30° C., and a solution obtained by dissolving 43.8 g of neodymium nitrate into 100 ml of methanol was dripped in while stirring. Upon completion of the dripping of the neodymium nitrate solution, it began to cloud, and the clouding increased with time. 30 minutes after completion of dripping, the solution was heated to 40° C. for 30 minutes, to produce a slurry solution of a neodymium salt of phenoxyacetic acid. Crystals obtained by filtering this slurry solution were added to 200 ml of methanol, stirred and washed, then refiltered, and 200 ml of methanol were once again added to the crystals, stirred and washed, then filtered. The resulting crystals were dried under reduced pressure at 50° C., to obtain 38.8 g of a neodymium salt of phenoxyacetic acid (yield 65%).

後処理

  1. customSpecifically, a reactor similar to that of 1-1 was used
  2. stirringto stir a solution
  3. customobtained
  4. temperatureby cooling in an ice water bath
  5. temperaturethe solution was heated for 30 minutes at 40° C.
  6. temperatureNext, this synthesis solution was maintained at about 30° C.
  7. customa solution obtained
  8. stirringwhile stirring
  9. temperaturethe clouding increased with time
  10. custom30 minutes
  11. temperaturethe solution was heated to 40° C. for 30 minutes

出典と根拠

ORDレコード
ord-f3aaec8856f24ac2b20a52a986e169b1
出典データセット
uspto-grants-2010_09
DOI
10.6084/m9.figshare.5104873.v1
特許番号
US07790290B2

反応ノート

読み込み中…

このページの内容参加物反応条件実験手順後処理出典と根拠反応ノート