Azido(trimethyl)stannane → HCID 178507543、化合物
反応式
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]#[N:10])=[CH:4][C:3]=1[C:11]1[CH2:16][CH2:15][CH2:14][CH2:13][CH:12]=1.[N:17]([Sn](C)(C)C)=[N+:18]=[N-:19]>C1(C)C=CC=CC=1>[C:11]1([C:3]2[CH:4]=[C:5]([CH2:8][C:9]3[NH:19][N:18]=[N:17][N:10]=3)[CH:6]=[CH:7][C:2]=2[NH2:1])[CH2:16][CH2:15][CH2:14][CH2:13][CH:12]=1参加物
4
実験手順
The title compound was prepared from (4-amino-3-cyclohex-1-enyl-phenyl)-acetonitrile (as prepared in the previous step, 103 mg, 0.485 mmol) and azidotrimethylstannane (105 mg, 0.510 mmol) in toluene (4 mL) according to the procedure in Example 52, step (c) and then further purified by preparative TLC (10% MeOH—CHCl3) to afford 40 mg (39%) as a white solid. Mass spectrum (ESI, m/z): Calcd. for C14H17N5, 256.1 (M+H), found 256.1.