1,2,4,5-Tetrafluorobenzene → (2,3,5,6-Tetrafluorophenyl)methanamine
反応式
[F:1][C:2]1[C:7]([C:8]#[N:9])=[C:6]([F:10])[C:5]([F:11])=[C:4](C#N)[C:3]=1[F:14].FC1C(C=O)=C(F)C(F)=C(C=O)C=1F.FC1C(F)=CC(F)=C(F)C=1.FC1C(F)=CC(F)=C(F)C=1C#N>>[F:1][C:2]1[C:3]([F:14])=[CH:4][C:5]([F:11])=[C:6]([F:10])[C:7]=1[CH2:8][NH2:9]参加物
5
実験手順
From the toluene extract, a small amount of a sample was withdrawn, and it was subjected to GC analysis. As a result of the analysis, a peak of the tetrafluoroterephthalonitrile as a raw material was below the detection limit, the amount of tetrafluoroterephthalaldehyde was 87.5 mol %, the amount of 2,3,5,6-tetrafluorobenzene was 2.00 mol %, and the amount of 2,3,5,6-tetrafluorobenzonitrile was 1.61 mol %. On the other hand, the aqueous phase was neutralized and then subjected to GC analysis. As a result of the analysis, presence of 2.16 mol % of 2,3,5,6-tetrafluorobenzylamine was confirmed. The results are set forth in Table 1.