Butaclamol → Dopamine

HRID 1712869

反応式

HRID 1712869 の反応式
C[N:2]1[CH2:12][C@H:11](C2C=CC=CC=2)[C:10]2[CH:9]=[C:8]([OH:19])[C:7](Cl)=[CH:6][C:5]=2CC1.CC([C@]1([OH:47])C[C@H]2N(C[C@H]3C4C2=CC=CC=4CCC2C=CC=CC3=2)CC1)(C)C>>[NH2:2][CH2:12][CH2:11][C:10]1[CH:5]=[CH:6][C:7]([OH:47])=[C:8]([OH:19])[CH:9]=1

参加物

3

反応物 2

HCID 37461ButaclamolHCID 3036864R-(+)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepine-7-ol

生成物 1

HCID 681Dopamine

実験手順

HEK cells were transfected with DNA encoding D1-NLS-GFP (2 micrograms), and D1-WT (6 micrograms) for 48 hours. These cells were treated 6 hrs after transfection with SCH-23390 (10 micromolar), or (+)butaclamol (10 micromolar). The medium containing antagonist was changed at 6, 22, 30 and 42 hours after transfection. Control cells received no antagonist treatment.

後処理

  1. additionThe medium containing antagonist
  2. customwas changed at 6, 22, 30 and 42 hours

出典と根拠

ORDレコード
ord-a3f9fc04036e44f4afbc9730448073af
出典データセット
uspto-grants-2010_09
特許番号
US07794955B2

関連ノート

読み込み中…