Methyl oxo{[4-(propylsulphonyl)phenyl]amino}acetate → 2-hydrazino-2-oxo-N-[4-(propylsulfonyl)phenyl]acetamide
反応式
[NH:1]([C:3](=[O:24])[C:4]([NH:6][C:7]1[CH:12]=[CH:11][C:10]([C@H]2CC[C@H](CC(OC)=O)CC2)=[CH:9][CH:8]=1)=[O:5])[NH2:2].O=C(NC1C=C[C:35]([S:38](CCC)(=[O:40])=[O:39])=[CH:34][CH:33]=1)C(OC)=O>>[NH:1]([C:3](=[O:24])[C:4]([NH:6][C:7]1[CH:8]=[CH:9][C:10]([S:38]([CH2:35][CH2:34][CH3:33])(=[O:40])=[O:39])=[CH:11][CH:12]=1)=[O:5])[NH2:2]参加物
3
実験手順
The procedure described for Intermediate 43 (part iv) was followed starting with methyl oxo{[4-(propylsulphonyl)phenyl]amino}acetate to give the title compound (Intermediate 97); 1H NMR δ 0.85-0.97 (m, 3H), 1.46-1.65 (m, 2H), 3.18-3.27 (m, 2H), 4.77 (s, 2H), 7.85 (d, 2H), 8.10 (d, 2H), 10.44 (s, 1H), 11.09 (s, 1H); MS m/e MH+ 286.
出典と根拠
- ORDレコード
- ord-62966620831e4f8dbb29044bb20e8ceb
- 出典データセット
- uspto-grants-2010_09
- 特許番号
- US07795283B2
反応ノート
読み込み中…