Ammonia → N-(2,2-Dimethoxyethyl)thiourea
反応式
[NH3:1].[CH3:2][O:3][CH:4]([O:9][CH3:10])[CH2:5][N:6]=[C:7]=[S:8]>CO>[CH3:2][O:3][CH:4]([O:9][CH3:10])[CH2:5][NH:6][C:7]([NH2:1])=[S:8]参加物
4
実験手順
Methanol (200 mL) was saturated with ammonia and stirred with isothiocyanatoacetaldehyde dimethyl acetal (5.0 g) for 2 h. The mixture was concentrated and the residue was chromatographed (silica gel, 5% methanol/dichloromethane) to give the title compound.
後処理
- concentrationThe mixture was concentrated
- customthe residue was chromatographed (silica gel, 5% methanol/dichloromethane)
出典と根拠
- ORDレコード
- ord-37d4e94f18a64572955158f797a738e8
- 出典データセット
- uspto-grants-1998_03
- 特許番号
- US05726192
反応ノート
読み込み中…