Hydrochloric Acid → HCID 67442415、化合物
反応式
Cl.[OH:2][C@@H:3]1[C@H:7]2[N:8](C(OC(C)(C)C)=O)[CH2:9][C@H:10]([S:11][CH3:12])[C@H:6]2[O:5][CH2:4]1>O1CCOCC1>[CH3:12][S:11][C@H:10]1[CH2:9][NH:8][C@@H:7]2[C@@H:3]([OH:2])[CH2:4][O:5][C@H:6]12参加物
4
実験手順
A solution of HCl in 1,4-dioxane (4M, 5.5 mL) was added to thiomethylether (54) (152 mg, 0.55 mmol). The mixture stirred for 1 hour then the solvents removed in vacuo. The residue was azeotroped with CH3CN (5 mL) to obtain (3R,3aR,6S,6aS)-6-(methylthio)hexahydro-2H-furo[3,2-b]pyrrol-3-ol which was used without further purification.
後処理
- customthe solvents removed in vacuo
- customThe residue was azeotroped with CH3CN (5 mL)
出典と根拠
- ORDレコード
- ord-1e8f0f7f834e4e06988dedbeeb095749
- 出典データセット
- uspto-grants-2010_09
- 特許番号
- US07799791B2
反応ノート
読み込み中…