Hydrochloric Acid → HCID 67410831、化合物

HRID 1715632ノート

反応式

HRID 1715632 の反応式
[ClH:1].[CH3:2][O:3][C:4](=[O:22])[C@@H:5]([NH:14]C(OC(C)(C)C)=O)[CH2:6][CH2:7][N:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1>>[ClH:1].[ClH:1].[CH3:2][O:3][C:4](=[O:22])[C@@H:5]([NH2:14])[CH2:6][CH2:7][N:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1

参加物

3

反応物 2

HCID 313Hydrochloric AcidHCID 67412729HCID 67412729、化合物

生成物 1

HCID 67410831HCID 67410831、化合物収率 46%

実験手順

HCl (0.45 mL of 4M in dioxane) was added to (S)-2-tert-Butoxycarbonylamino-4-piperidin-1-yl-butyric acid methyl ester and the mixture was stirred at room temperature for 2 hours. The reaction mixture was concentrated under reduced pressure and dried under high vacuum for 16 hours to provide the product (46% yield).

後処理

  1. concentrationThe reaction mixture was concentrated under reduced pressure
  2. customdried under high vacuum for 16 hours

出典と根拠

ORDレコード
ord-8f419218be01454884c365da99ec4d3e
出典データセット
uspto-grants-2010_09
特許番号
US07799782B2

反応ノート

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