1,2,3,4-Tetrahydroquinoline → HCID 42886374、化合物

HRID 1716250ノート

反応式

HRID 1716250 の反応式
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10][CH:11]([CH3:15])[C:12]([OH:14])=O.[NH:16]1[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH2:19][CH2:18][CH2:17]1>>[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10][CH:11]([CH3:15])[C:12]([N:16]1[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH2:19][CH2:18][CH2:17]1)=[O:14]

参加物

3

反応物 2

HCID 694601,2,3,4-TetrahydroquinolineHCID 29022242-[(1,3-Benzothiazol-2-yl)sulfanyl]propanoic acid

生成物 1

HCID 42886374HCID 42886374、化合物収率 34%

実験手順

The title compound was synthesized according to General Procedure B using 2-(benzo[d]thiazol-2-ylthio)propanoic acid and 1,2,3,4-tetrahydroquinoline to yield 47 as a yellow oil (34%): MS m/z: 355 (M+H)+. Anal. Calcd. For, C19H18N2OS2: C, 64.38; H, 5.12; N, 7.90; S, 18.09. Found: C, 64.38; H, 5.26; N, 7.97; S, 18.08.

後処理

  1. customThe title compound was synthesized

出典と根拠

ORDレコード
ord-ff4f3c04481c4339954f5c50286363e5
出典データセット
uspto-grants-2010_09
特許番号
US07803790B2

反応ノート

読み込み中…