(4-Methoxyphenyl)boronic acid → 3-(1H-Indol-6-yl)-3-(4-methoxy-phenyl)-propionic acid methyl ester
反応式
B(O)(O)[C:2]1[CH:3]=[CH:4][C:5]([O:8][CH3:9])=[CH:6][CH:7]=1.[CH3:12][O:13][C:14](=[O:34])[CH2:15][CH:16]([C:25]1[CH:33]=[C:32]2[C:28]([CH:29]=[CH:30][NH:31]2)=[CH:27][CH:26]=1)C1C=CC=C(OC)C=1>>[CH3:12][O:13][C:14](=[O:34])[CH2:15][CH:16]([C:25]1[CH:33]=[C:32]2[C:28]([CH:29]=[CH:30][NH:31]2)=[CH:27][CH:26]=1)[C:2]1[CH:3]=[CH:4][C:5]([O:8][CH3:9])=[CH:6][CH:7]=1参加物
3
実験手順
3-(1H-Indol-6-yl)-3-(4-methoxy-phenyl)-propionic acid methyl ester XXXIV (0.51 g, 66% yield) was prepared from 4-methoxy boronic acid using the procedure described for preparation of 3-(1H-indol-6-yl)-3-(3-methoxy-phenyl)-propionic acid methyl ester XXXI (see Example 7).
出典と根拠
- ORDレコード
- ord-f25fc73ff7b742358e68d47c5794e9c8
- 出典データセット
- uspto-grants-2010_09
- 特許番号
- US07803830B2