3-(3-cyano-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl ester → 3-(1H-Indazol-4-yl)-N-methyl-3-phenyl-acrylamide
反応式
C([O:3][C:4](=O)[CH:5]=[C:6]([C:13]1[CH:21]=[CH:20][CH:19]=[C:18]2[C:14]=1[CH:15]=[N:16][NH:17]2)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)C.C(OC(=O)C=C(C1C=CC=C2C=1C(C#N)=[CH:38][NH:39]2)C1C=CC=CC=1)C>>[NH:17]1[C:18]2[C:14](=[C:13]([C:6]([C:7]3[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=3)=[CH:5][C:4]([NH:39][CH3:38])=[O:3])[CH:21]=[CH:20][CH:19]=2)[CH:15]=[N:16]1参加物
3
実験手順
3-(1H-Indazol-4-yl)-N-methyl-3-phenyl-acrylamide CXCII was prepared from 3-(1H-indazol-4-yl)-3-phenyl-acrylic acid ethyl ester using the procedure described for preparation of 3-(1H-Indol-7-yl)-N-methyl-3-phenyl-acrylamide XVIII (see Example 4).
出典と根拠
- ORDレコード
- ord-994d71ccbb05416dbd99b21f3e78dd69
- 出典データセット
- uspto-grants-2010_09
- 特許番号
- US07803830B2
反応ノート
読み込み中…