1-(2,4-Dihydroxy-3-methylphenyl)ethan-1-one → 1-{2-Hydroxy-4-[3-(4-iodo-benzyl)-[1,2,4]oxadiazol-5-ylmethoxy]-3-methyl-phenyl}-ethanone
反応式
[OH:1][C:2]1[C:7]([CH3:8])=[C:6]([O:9][CH2:10][C:11]2[O:15][N:14]=[C:13]([CH2:16][C:17]3[CH:22]=[CH:21][CH:20]=[C:19](I)[CH:18]=3)[N:12]=2)[CH:5]=[CH:4][C:3]=1[C:24](=[O:26])[CH3:25].ClCC1ON=C(CC2C=CC([I:41])=CC=2)N=1.OC1C(C)=C(O)C=CC=1C(=O)C>>[OH:1][C:2]1[C:7]([CH3:8])=[C:6]([O:9][CH2:10][C:11]2[O:15][N:14]=[C:13]([CH2:16][C:17]3[CH:22]=[CH:21][C:20]([I:41])=[CH:19][CH:18]=3)[N:12]=2)[CH:5]=[CH:4][C:3]=1[C:24](=[O:26])[CH3:25]参加物
4
反応物 3
生成物 1
実験手順
The title compound is prepared essentially as described for 1-{2-hydroxy-4-[3-(3-iodo-benzyl)-[1,2,4]oxadiazol-5-ylmethoxy]-3-methyl-phenyl}-ethanone, employing 5-chloromethyl-3-(4-iodo-benzyl)-[1,2,4]oxadiazole and 1-(2,4-Dihydroxy-3-methyl-phenyl)-ethanone. LC-MS (m/e): 463 (M−1).
出典と根拠
- ORDレコード
- ord-1d6dfa4a0e5a4e259375aa00254f14a9
- 出典データセット
- uspto-grants-2010_09
- 特許番号
- US07803938B2
反応ノート
読み込み中…