Potassium Carbonate → [[7-(2-Propenyloxy)-2-naphthalenyl]oxy]acetic acid methyl ester

HRID 1719420ノート

反応式

HRID 1719420 の反応式
[CH2:1]([O:4][C:5]1[CH:14]=[C:13]2[C:8]([CH:9]=[CH:10][C:11]([OH:15])=[CH:12]2)=[CH:7][CH:6]=1)[CH:2]=[CH2:3].C(=O)([O-])[O-].[K+].[K+].Br[CH2:23][C:24]([O:26][CH3:27])=[O:25]>CC(C)=O>[CH3:27][O:26][C:24](=[O:25])[CH2:23][O:15][C:11]1[CH:10]=[CH:9][C:8]2[C:13](=[CH:14][C:5]([O:4][CH2:1][CH:2]=[CH2:3])=[CH:6][CH:7]=2)[CH:12]=1

参加物

5

反応物 3

HCID 11430Potassium CarbonateHCID 60984Methyl bromoacetateHCID 111716387-(2-Propenyloxy)-2-naphthalenol

生成物 1

HCID 13504790[[7-(2-Propenyloxy)-2-naphthalenyl]oxy]acetic acid methyl ester

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

A mixture of 7.9 g of 7-(2-propenyloxy)-2-naphthalenol and 8.3 g of potassium carbonate in 50 ml of anhydrous acetone was stirred at room temperature for 1.5 hours. Methyl bromoacetate (4.7 ml) was added and stirring was continued for 18 hours. The reaction mixture was filtered and the filtrate was concentrated in vacuo to yield (8.4 g) of [[7-(2-propenyloxy)-2-naphthalenyl]oxy]acetic acid methyl ester, mp 69°-70° after recrystallization from ether-hexane.

後処理

  1. stirringstirring
  2. waitwas continued for 18 hours
  3. filtrationThe reaction mixture was filtered
  4. concentrationthe filtrate was concentrated in vacuo

出典と根拠

ORDレコード
ord-673b2ab29fa94bdd84bfa460d4d30862
出典データセット
uspto-grants-1985_09
特許番号
US04539419

反応ノート

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