2,4'-Dichlorobenzophenone → 2-Chlorobenzoyl chloride

HRID 1719635

反応式

HRID 1719635 の反応式
[N+]([C:4]1[CH:5]=[C:6]([C:19]([Cl:22])=[CH:20][CH:21]=1)[C:7](C1C=CC(Cl)=C([N+]([O-])=O)C=1)=[O:8])([O-])=O.[Cl:23]C1C=CC=CC=1C(C1C=CC(Cl)=CC=1)=O>ClC1C=CC=CC=1>[Cl:22][C:19]1[CH:20]=[CH:21][CH:4]=[CH:5][C:6]=1[C:7]([Cl:23])=[O:8]

参加物

4

反応物 2

HCID 665582,4'-DichlorobenzophenoneHCID 230560(2-Chloro-5-nitrophenyl)(4-chloro-3-nitrophenyl)methanone

生成物 1

HCID 691102-Chlorobenzoyl chloride

試薬・触媒・溶媒 1

HCID 7964Chlorobenzene溶媒

実験手順

For example, 3,3'-dinitro-4,4'-dichlorobenzophenone can be prepared in a yield of 95 to 98% by nitrating 4,4'-dichlorobenzophenone [E. R. Kofanov et al., J. Org. Chem. USSR, 15, 98-100 (1979)]. 5,3'-Dinitro-2,4'-dichlorobenzophenone can be prepared in a high yield by nitrating 2,4'-dichlorobenzophenone [E. H. Faith et al., J. Am. Chem. Soc., 77, 543 (1955)]. 3,3'-Dinitro-4-chlorobenzophenone can be prepared in a high yield by nitrating 4-chlorobenzophenone [G. S. Mironov et al., J. Org. Chem. USSR, 8, 1538 (1972)]. 3,4'-Dinitro-4-chlorobenzophenone can be prepared by nitrating 4-halogeno-4'-nitrobenzophenone obtained by the condensation reaction between p-nitrobenzoyl chloride and chlorobenzene [P. T. Montagne et al., Ber., 49, 2267-2270 (1916); G. S. Mironov et al., J. Org. Chem. USSR, 8, 1538-1543 (1972)]. 3,3'-Dinitro-6,4'-dichlorobenzophenone can be prepared in a high yield by nitrating 2,4'-dichlorobenzophenone obtained by the condensation reaction between 2-chlorobenzoyl chloride and chlorobenzene [H. F. Faith et al., J. Am. Chem. Soc., 77, 543 (1955)].

後処理

  1. customa high yield

出典と根拠

ORDレコード
ord-9f0b35368a7b40fab62f61dce995e5e0
出典データセット
uspto-grants-1985_09
特許番号
US04540818

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