Methylhydrazine → N-methylbenzohydrazide
反応式
[CH3:1][NH:2][NH2:3].[C:4](Cl)(=[O:11])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1>ClCCl>[C:4]([N:2]([CH3:1])[NH2:3])(=[O:11])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1参加物
4
実験手順
Methylhydrazine (0.212 ml, 4.0 mmol) was dissolved in dichloromethane (10 ml) and was treated dropwise with benzoylchloride (0.232 ml, 2.0 mmol) in dichloromethane (5 ml). After stirring for 0.5h the solution was evaporated to dryness. The residue was partitioned between water and ethyl acetate. The organic phase was dried and evaporated under reduced pressure to give the title compound (0.20 g, 65%); δH (CDCl3) 3.13 (3H, s), 4.5 (2H, brs), and 7.30 (5H, s).
後処理
- customwas evaporated to dryness
- customThe residue was partitioned between water and ethyl acetate
- customThe organic phase was dried
- customevaporated under reduced pressure
出典と根拠
- ORDレコード
- ord-64901f962b6946c588844917b5af40ea
- 出典データセット
- uspto-grants-1996_04
- 特許番号
- US05504076
反応ノート
読み込み中…