Dodecylamine → 4-Dodecylamino-2-methylquinolin-6-ol Hydrochloride Hydrate

反応式

[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([OH:12])[CH:10]=2)[N:5]=[C:4]([CH3:13])[CH:3]=1.[CH2:14]([NH2:26])[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]>>[OH2:12].[ClH:1].[CH2:14]([NH:26][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([OH:12])[CH:10]=2)[N:5]=[C:4]([CH3:13])[CH:3]=1)[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]

参加物

反応物 2

HCID 13583Dodecylamine

HCID 7715204-Chloro-2-methylquinolin-6-ol

生成物 1

HCID 224178954-Dodecylamino-2-methylquinolin-6-ol Hydrochloride Hydrate

実験手順

In a manner similar to that described in Example 39, Part B, 4-chloro-2-methylquinolin-6-ol and dodecylamine were transformed into the title compound: m.p. 198°-203° C.

出典と根拠

ORDレコード: ord-0406f560f11f4d4a92e8a6f2d1150949
出典データセット: uspto-grants-1996_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05506235

反応ノート

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