4-(Cyclohexylmethoxy)aniline → 4-[4-(cyclohexylmethyloxy)phenylamino]quinolin-8-ol Hydrochloride Hydrate
反応式
Br.[Cl:2][C:3]1[C:12]2[C:7](=[C:8]([OH:13])[CH:9]=[CH:10][CH:11]=2)[N:6]=[CH:5][CH:4]=1.[CH:14]1([CH2:20][O:21][C:22]2[CH:28]=[CH:27][C:25]([NH2:26])=[CH:24][CH:23]=2)[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1>>[OH2:13].[ClH:2].[CH:14]1([CH2:20][O:21][C:22]2[CH:28]=[CH:27][C:25]([NH:26][C:3]3[C:12]4[C:7](=[C:8]([OH:13])[CH:9]=[CH:10][CH:11]=4)[N:6]=[CH:5][CH:4]=3)=[CH:24][CH:23]=2)[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]1参加物
3
実験手順
In a manner similar to that described in Example 46, Part B, 4-chloro-quinolin-8-ol hydrobromide and 4-(cyclohexylmethyloxy)aniline were tranformed into and the title product: m.p. 286°-288° C. (from methanol-acetonitrile).
出典と根拠
- ORDレコード
- ord-e3c21f3082f24bbb925b62b0eea9dc76
- 出典データセット
- uspto-grants-1996_04
- 特許番号
- US05506235
反応ノート
読み込み中…