Methanethiol → Ethyl 2-ethylthiomethyl-4-methylpentanoate
反応式
[CH2:1]([C:5](=[CH2:11])[C:6]([O:8][CH2:9][CH3:10])=[O:7])[CH:2]([CH3:4])[CH3:3].C[C:13]([CH3:16])([O-])C.[K+].C[SH:19]>C(OCC)(=O)C>[CH2:13]([S:19][CH2:11][CH:5]([CH2:1][CH:2]([CH3:4])[CH3:3])[C:6]([O:8][CH2:9][CH3:10])=[O:7])[CH3:16]参加物
5
実験手順
650 mg of ethyl 2-isobutyl-2-propenoate was dissolved in 3 ml of methylmercaptan, and 50 mg of potassium tert-butoxide was added thereto. The mixture was stirred at room temperature for two hours. The reaction solution was diluted with 60 ml of ethyl acetate, washed with water and then with a saturated sodium chloride aqueous solution and dried over anhydrous sodium sulfate. The solvent was distilled off under reduced pressure to obtain 660 mg of ethyl 2-ethylthiomethyl-4-methylpentanoate as colorless oily substance.
後処理
- washwashed with water
- dry with materialwith a saturated sodium chloride aqueous solution and dried over anhydrous sodium sulfate
- distillationThe solvent was distilled off under reduced pressure
出典と根拠
- ORDレコード
- ord-b260e60e8d42432c9ae1c67fa8bcd51f
- 出典データセット
- uspto-grants-1996_04
- 特許番号
- US05506356
反応ノート
読み込み中…