Hydrochloric Acid → HCID 70094289、化合物
反応式
[CH2:1]([O:3][C:4](=[O:28])[C@H:5]([CH2:20][C:21]1[CH:26]=[CH:25][C:24]([OH:27])=[CH:23][CH:22]=1)[NH:6][C:7](=[O:19])[C:8]([NH:11]C(OC(C)(C)C)=O)([CH3:10])[CH3:9])[CH3:2].[ClH:29]>C(OCC)(=O)C.CO>[ClH:29].[CH2:1]([O:3][C:4](=[O:28])[C@H:5]([CH2:20][C:21]1[CH:22]=[CH:23][C:24]([OH:27])=[CH:25][CH:26]=1)[NH:6][C:7](=[O:19])[C:8]([NH2:11])([CH3:10])[CH3:9])[CH3:2]参加物
5
実験手順
Into a stirred solution of N-[2-(t-butoxycarbonylamino)-2-methyl-1-oxopropyl]-L-tyrosine ethyl ester (1.46 g, 3.70 mmol) in ethyl acetate (50 mL) and methanol (10 mL) is bubbled hydrochloric acid gas for 10 minutes. The solvent is removed to give N-(2-amino-2-methyl-1-oxopropyl)-L-tyrosine ethyl ester monohydrochloride as a white foam which is used without any further purification.