化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → N-(1-Methyl-5-indolyl)-N'-(4-isoquinolyl) urea
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| 反応物 | 4-Aminoisoquinoline | HCID 90237 | — |
| 反応物 | 1-methyl-1H-indol-5-amine | HCID 2769564 | — |
| 溶媒 | Diethyl ether ethanol | HCID 21585056 | — |
| 生成物 | N-(1-Methyl-5-indolyl)-N'-(4-isoquinolyl) urea | HCID 22416532 | — |
反応手順
The title compound was prepared from 4-aminoisoquinoline, 1,1'-carbonyl diimidazole and 5-amino-1-methyl-indole using a procedure similar to that described for Example 1, and then converted to the hydrochloride salt using hydrogen chloride in ether/ethanol, in 26% overall yield, m.p. 195°-197° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05508288 |
| 出典データセット | uspto-grants-1996_04 |
| ORD ID | ord-215ab40df9634630af5f9a7d20aca993 |
| 出典メモ | uspto-grants-1996_04 |