関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Tert-Butylamine | HCID 6385 | — |
| 反応物 | 1-[4-(2-Chloroethoxy)phenyl]ethanone | HCID 13691191 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 1-[4-{-2-(1,1-Dimethylethylamino)-ethoxy}-phenyl]-ethanone | HCID 13691192 | — |
反応手順
A mixture of 6.5 g of the product of Step A in 30 ml of tert.-butylamine was heated at 120° C. for 30 hours and was then diluted with water and extracted with ethyl acetate. The organic phase was washed with water, dried over a deshydrant, filtered and evaporated to dryness. The residue was chromatographed over silica and eluted with a 9-1 ethyl acetate-triethylamine mixture to obtain 7.264 g of 1-[4-{-2-(1,1-dimethylethylamino)-ethoxy}-phenyl]-ethanone.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04853408 |
|---|
| 出典データセット | uspto-grants-1989_08 |
|---|
| ORD ID | ord-fca304eb29c24e84bbfaa78ddfa3439e |
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| 出典メモ | uspto-grants-1989_08 |
|---|
