5-Phenyl-4-pentyn-1-ol → 4-Pentynal, 5-phenyl-

HRID 1722217ノート

反応式

HRID 1722217 の反応式
[C:1]1([C:7]#[C:8][CH2:9][CH2:10][CH2:11][OH:12])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>C(Cl)Cl.CCOCC>[C:1]1([C:7]#[C:8][CH2:9][CH2:10][CH:11]=[O:12])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

5

反応物 2

HCID 111374345-Phenyl-4-pentyn-1-olHCID 178418287HCID 178418287、化合物

生成物 1

HCID 112406334-Pentynal, 5-phenyl-

試薬・触媒・溶媒 2

HCID 3283Diethyl Ether溶媒HCID 6344Dichloromethane溶媒2 回

実験手順

A solution of 5-phenylpent-4-yn-1-ol (250 mg) in dry CH2Cl2 (2 ml) was added to a suspension of pyridinium chlorochromate (520 mg) in dry CH2Cl2 (3 ml). The mixture was stirred for 2.5 hours and diluted with ether, and the organic solution was decanted off. The oily residue was treated with ether (5×20 ml) and the extracts were washed successively with 5% NaHCO3, water and brine. After drying, the solvent was removed to yield 5-phenylpent-4-ynal.

後処理

  1. customthe organic solution was decanted off
  2. additionThe oily residue was treated with ether (5×20 ml)
  3. washthe extracts were washed successively with 5% NaHCO3, water and brine
  4. customAfter drying
  5. customthe solvent was removed

出典と根拠

ORDレコード
ord-417280dbb81b4e1cb4f39d4744db33db
出典データセット
uspto-grants-1989_08
特許番号
US04855086

反応ノート

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