Acetic Anhydride → HCID 15051750、化合物
反応式
[OH:1][C:2]1[CH:3]=[C:4]([CH:19]=[O:20])[CH:5]=[C:6]2[C:14]=1[CH:13]([CH2:15][OH:16])[C:12]1([OH:18])[O:17][N:7]2[CH2:8][CH:9]2[CH:11]1[NH:10]2.[C:21](OC(=O)C)(=[O:23])[CH3:22]>CO>[C:21]([N:10]1[CH:9]2[CH:11]1[C:12]1([OH:18])[O:17][N:7]([CH2:8]2)[C:6]2[C:14](=[C:2]([OH:1])[CH:3]=[C:4]([CH:19]=[O:20])[CH:5]=2)[CH:13]1[CH2:15][OH:16])(=[O:23])[CH3:22]参加物
4
実験手順
To a solution of 6,9-dihydroxy-8-hydroxymethyl-14-oxa-1,11-diazatetracyclo[7.4.1.02,7.010,12 ]tetradeca-2,4,6-triene-4-carbaldehyde (98 mg) in methanol (3 ml) was added acetic anhydride (40 μl). The mixture was stirred for 1 hour at ambient temperature and evaporated in vacuo. The residue was subjected to preparative thin layer chromatography, which was developed with a mixture of chloroform and methanol (10:1, v/v) to afford 11-acetyl-6,9-dihydroxy-8-hydroxymethyl-14-oxa-1,11-diazatetracyclo[7.4.1.02,7.010,12 ]tetradeca-2,4,6-triene-4-carbaldehyde (71 mg).