Hydrochloric Acid → 2-Chloro-4,6-di-p-tolyl-1,3,5-triazine

HRID 1724088

反応式

HRID 1724088 の反応式
[N:1]1[C:8](Cl)=[N:7][C:5](Cl)=[N:4][C:2]=1[Cl:3].[Cl-].[Al+3].[Cl-].[Cl-].Cl.[C:15]1([CH3:21])[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>ClC1C=CC=CC=1Cl>[Cl:3][C:2]1[N:4]=[C:5]([C:18]2[CH:19]=[CH:20][C:15]([CH3:21])=[CH:16][CH:17]=2)[N:7]=[C:8]([C:18]2[CH:19]=[CH:20][C:15]([CH3:21])=[CH:16][CH:17]=2)[N:1]=1

参加物

6

反応物 4

HCID 313Hydrochloric AcidHCID 1140TolueneHCID 7954Cyanuric chlorideHCID 6451240Aluminum(III) Chloride

生成物 1

HCID 308512-Chloro-4,6-di-p-tolyl-1,3,5-triazine

試薬・触媒・溶媒 1

HCID 72391,2-Dichlorobenzene溶媒

実験手順

To a stirring mixture of 1 eq of cyanuric chloride and 3 eq of aluminum chloride in o-dichlorobenzene at ice bath temperature was added concentrated HCl (13 wt % based on cyanuric chloride). After 10 minutes, 1.9 eq of toluene was added and the reaction mixture was stirred at ice bath temperature for 30 minutes. The cooling bath was removed, the reaction mixture was allowed to warm to room temperature, and stirred for 21 h. HPLC analysis indicated about 95% cyanuric chloride conversion to 2-chloro-4,6-bis(4-methylphenyl)-1,3,5-triazine and the isomer 2-chloro-4-(4-methylphenyl)-6-(2-methylphenyl)-1,3,5-triazine

後処理

  1. customThe cooling bath was removed
  2. stirringstirred for 21 h

出典と根拠

ORDレコード
ord-0aced62d3bda4e49aa263edc42c1b467
出典データセット
uspto-grants-2009_02
特許番号
US07485723B2

関連ノート

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