3-(Methylamino)-1-(thiophen-2-yl)propan-1-one → (s)-3-(methylamino)-1-phenylpropanol (114133-37-8)

HRID 1725090

反応式

HRID 1725090 の反応式
[CH3:1][NH:2][CH2:3][CH2:4][C@@H:5]([C:7]1S[CH:9]=[CH:10][CH:11]=1)[OH:6].CN[CH2:14][CH2:15]C(C1SC=CC=1)=O>>[CH3:1][NH:2][CH2:3][CH2:4][C@@H:5]([C:7]1[CH:15]=[CH:14][CH:9]=[CH:10][CH:11]=1)[OH:6]

参加物

3

反応物 2

HCID 100358733-(Methylamino)-1-(thiophen-2-yl)propan-1-oneHCID 100950473-(N-Methylamino)-1-(2-thienyl)-1-propanol, (-)-

生成物 1

HCID 7439089(s)-3-(methylamino)-1-phenylpropanol (114133-37-8)

実験手順

In particular, it opens up the possibility of obtaining enantiomerically pure or enantiomerically enriched (S)-3-methylamino-1-(2-thienyl)-1-propanol in a simple manner starting from 3-methylamino-1-(2-thienyl)-1-propanone. Likewise, enantiomerically pure or enantiomerically enriched (S)-3-methylamino-1-phenyl-1-propanol can be obtained in a simple manner starting from 3-methylamino-1-phenyl-1-propanone.

後処理

  1. customof obtaining enantiomerically pure

出典と根拠

ORDレコード
ord-9907bd4345f14f92b26fc1cca479a64d
出典データセット
uspto-grants-2009_02
特許番号
US07488833B2

関連ノート

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