Diethyl(2-isothiocyanatoethyl)amine → 8-(2-Diethylaminoethyl)thiocarbamoylamino-3-methyl-5,6,7,8-tetrahydroquinoline

反応式

[NH2:1][CH:2]1[C:11]2[N:10]=[CH:9][C:8]([CH3:12])=[CH:7][C:6]=2[CH2:5][CH2:4][CH2:3]1.[CH2:13]([N:15]([CH2:18][CH2:19][N:20]=[C:21]=[S:22])[CH2:16][CH3:17])[CH3:14]>>[CH2:13]([N:15]([CH2:16][CH3:17])[CH2:18][CH2:19][NH:20][C:21]([NH:1][CH:2]1[C:11]2[N:10]=[CH:9][C:8]([CH3:12])=[CH:7][C:6]=2[CH2:5][CH2:4][CH2:3]1)=[S:22])[CH3:14]

参加物

反応物 2

HCID 2772281Diethyl(2-isothiocyanatoethyl)amine

HCID 123582203-Methyl-5,6,7,8-tetrahydroquinolin-8-amine

生成物 1

HCID 214987878-(2-Diethylaminoethyl)thiocarbamoylamino-3-methyl-5,6,7,8-tetrahydroquinoline

実験手順

8-amino-3-methyl-5,6,7,8-tetrahydroquinoline may be treated with diethylaminoethyl isothiocyanate according to the procedure of Example 4 to give the title compound.

出典と根拠

ORDレコード: ord-7c51b101f21642fbb7719120d97cc98f
出典データセット: uspto-grants-1976_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US03991065

反応ノート

読み込み中…