化工社化工社 化学情報印刷レポート · 研究参考用
Sodium Hydroxide → Ethnor
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate sulfate | HCID 3084993 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Ethnor | HCID 36339 | — |
反応手順
A solution of 47.5 parts of (-)-ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate sulfate in 500 parts of water is alkalized with 14 parts of a sodium hydroxide solution 50%. The product is extracted twice with 325 parts of dichloromethane. The combined extracts are dried, filtered and evaporated in vacuo. The residue is crystallized from 2,2'-oxybispropane, yielding (-)-ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03991072 |
| 出典データセット | uspto-grants-1976_11 |
| ORD ID | ord-5bdca24f7ac64c88b979240b23bff893 |
| 出典メモ | uspto-grants-1976_11 |