Propan-2-ylcarbamyl chloride → Carbamic chloride

HRID 1730099ノート

反応式

HRID 1730099 の反応式
[CH:1]([NH:4][C:5]([Cl:7])=[O:6])([CH3:3])[CH3:2]>ClC1C=CC=CC=1>[CH:1]([N:4]=[C:5]=[O:6])([CH3:3])[CH3:2].[C:5]([Cl:7])(=[O:6])[NH2:4]

参加物

4

反応物 1

HCID 12681864Propan-2-ylcarbamyl chloride

生成物 2

HCID 61277Isopropyl isocyanateHCID 68048Carbamic chloride収率 93%

試薬・触媒・溶媒 1

HCID 7964Chlorobenzene溶媒

実験手順

A solution of 970 parts of isopropylcarbamic acid chloride in 1,020 parts of chlorobenzene is inroduced into an apparatus analogous to that of Example 1 and is refluxed for 9 hours -- during which the reaction temperature rises from 77° to 88° C -- whilst passing 120,000 parts by volume of dry nitrogen per hour through the mixture. The subsequent distillation gives 630 parts of isopropyl isocyanate free from carbamic acid chloride (corresponding to 93% of theory, based on isopropylcarbamic acid chloride used), boiling at from 73.5° to 74.5° C.

後処理

  1. temperatureis refluxed for 9 hours
  2. customrises from 77° to 88° C
  3. distillationThe subsequent distillation

出典と根拠

ORDレコード
ord-f344c4760e4341239ed1ed0e958aa602
出典データセット
uspto-grants-1976_11
特許番号
US03991094

反応ノート

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