化工社化工社 化学情報印刷レポート · 研究参考用
Miconazole → HCID 178521218、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Miconazole | HCID 4189 | — |
| 反応物 | 2,4-Dichloro-alpha-(chloromethyl)benzenemethanol | HCID 94351 | — |
| 溶媒 | Benzonitrile | HCID 7505 | — |
| 生成物 | HCID 178521218 | HCID 178521218 | — |
反応手順
4.2 parts of 1-[2,4-dichloro-β-(2,4-dichlorobenzyloxy)phenethyl]imidazole and 3 parts of 2,4-dichloro-α-(chloromethyl)benzyl alcohol are mixed together in 40 parts of benzonitrile and the resulting mixture is stirred at reflux temperature for 3 days. At the end of this period the reaction solvent is evaporated off under reduced pressure to obtain a 1-[2,4-dichloro-β-(2,4-dichlorobenzyloxy)phenethyl]-3-(2,4dichloro-β-hydroxyphenethyl)imidazolium chloride product as residue.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03991202 |
| 出典データセット | uspto-grants-1976_11 |
| ORD ID | ord-b8c99004b2fc46d8abdd7b201cc6f99d |
| 出典メモ | uspto-grants-1976_11 |