2-Amino-4,5-dimethyl-1,3-thiazole → HCID 54695946、化合物

HRID 1730550ノート

反応式

HRID 1730550 の反応式
CO[C:3]([C:5]1[N:6]([CH3:22])[S:7](=[O:21])(=[O:20])[C:8]2[C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[CH:13]=[CH:12][C:9]=2[C:10]=1[OH:11])=[O:4].[NH2:23][C:24]1[S:25][C:26]([CH3:30])=[C:27]([CH3:29])[N:28]=1>C(Cl)CCl>[CH3:29][C:27]1[N:28]=[C:24]([NH:23][C:3]([C:5]2[N:6]([CH3:22])[S:7](=[O:21])(=[O:20])[C:8]3[C:19]4[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=4)[CH:13]=[CH:12][C:9]=3[C:10]=2[OH:11])=[O:4])[S:25][C:26]=1[CH3:30]

参加物

4

反応物 2

HCID 732382-Amino-4,5-dimethyl-1,3-thiazoleHCID 546906514-hydroxy-2-methyl-2H-naphtho[2,1-e]-1,2-thiazine-3-carboxylic acid methylester-1,1-dioxide

生成物 1

HCID 54695946HCID 54695946、化合物収率 31%

試薬・触媒・溶媒 1

HCID 111,2-Dichloroethane溶媒

実験手順

N-(4,5-Dimethyl-2-thiazolyl)-4-hydroxy-2-methyl-2 H-naphtho[2,1-e]-1,2-thiazine-3-carboxamide-1,1-dioxide was prepared analogous to Example 22 from 4-hydroxy-2-methyl-2H-naphtho[2,1-e]-1,2-thiazine-3-carboxylic acid methylester-1,1-dioxide and 2-amino-4,5-dimethyl-thiazole. Yield: 31% of theory; m.p. 264°-265° C (decomp.; from ethylene chloride).

出典と根拠

ORDレコード
ord-11366324faa147d7a89e0568828176d6
出典データセット
uspto-grants-1976_11
特許番号
US03992535

反応ノート

読み込み中…