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Acetic Acid → 3,5-Di-tert.butyl-4-hydroxybenzyl-malonic acid-bis(2,2,6,6-tetramethyl-4-piperidinyl)ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | Lithium amide | HCID 24532 | — |
| 反応物 | Phenol, 4-[(dimethylamino)methyl]-2,6-bis(1,1-dimethylethyl)- | HCID 66609 | — |
| 反応物 | Bis(2,2,6,6-tetramethylpiperidin-4-yl) propanedioate | HCID 1244568 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 3,5-Di-tert.butyl-4-hydroxybenzyl-malonic acid-bis(2,2,6,6-tetramethyl-4-piperidinyl)ester | HCID 14093876 | — |
反応手順
26 g (0.068 mole) of bis-(2,2,6,6-tetramethyl-4-piperidinyl) malonate and 17.8 g (0.068 mole) of N-(3,5-di-tert.butyl-4-hydroxybenzyl)dimethylamine are dissolved in 200 ml of toluene. After the addition of 0.5 g of lithium amide, the mixture is refluxed for 3 hours. After cooling, the mixture is neutralised with 1.5 ml of 1% acetic acid, and the organic phase repeatedly washed with water. After drying phase repeatedly washed with water. After drying over Na2SO4, the solution is concentrated in vacuo to obtain, as oily residue, 3,5-di-tert.butyl-4-hydroxybenzyl-malonic acid-bis(2,2,6,6-tetramethyl-4-piperidinyl)ester.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03993655 |
| 出典データセット | uspto-grants-1976_11 |
| ORD ID | ord-8fc656c33893467281e6e931b34dddb2 |
| 出典メモ | uspto-grants-1976_11 |